IP International Journal of Forensic Medicine and Toxicological Sciences

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Get Permission Rao, Fatima, and Kiran: Sudden natural deaths autopsies-An analytical study


Introduction

Death is said to be sudden or unexpected when a person not known to have been suffering from any dangerous disease, injury or poisoning is found dead or dies within 24 hours after the onset of terminal illness (WHO). Some authors limit sudden deaths as those occurring instantaneously or within one hour of onset of symptoms. Emphasis is placed more on the unexpected character, rather than suddenness of death. Natural death means that the death was caused entirely by the disease, and the trauma or poison did not play any part in bringing it about.1 The study of sudden death helps in establishing the precise causes of death and enable in assisting the legal authorities in detection of crime, improve the mortality statistical data and pacify the bereaved and aggrieved relatives where the medical negligence was the sufficient ground for legal proceedings.2 The incidence is approximately 10 percent of all deaths. No period in life is exempt.1 The Size of the population limited to the jurisdiction,Attibele, Bangalore Rural district of Karnataka state in India , to this autopsy study is around 1-1.5 lakhs. The group involved individuals of all age group, Sex, religion, caste and Nationality.

In the present study analysis of all the sudden deaths referred to Forensic Medicine Department of The Oxford Medical College, Bangalore was done in order to understand the prevalence of disease process responsible for the death of the individual.

Figure 1

Total sudden & natural death autopsies done in the present study.

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Figure 2

Sex group affected.

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Table 1

Age (years)

Male deaths

Female deaths

Total deaths

1-10

-

-

0

11-20

-

-

0

21-30

7

-

7 (13.5%)

31-40

10

1

11(21.15%)

41-50

20

1

21(40.38%)

51-60

5

-

5(9.61%)

61-70

2

2

4(7.69%)

71-80

3

-

3(5.57%)

81-90

1

-

1(1.92%)

Total (%)

48(92.3%)

4(7.69%)

52(100%)

Table 2

Systems affected

System affected

Male deaths

Female deaths

Total deaths

Percentage

Central Nervous System

01

01

3.84%

Cardio Vascular System

34

02

36

69.23%

Gastro Intestinal Tract

02

-

02

3.85%

Respiratory System

10

02

12

23.07%

Hepatobiliary System

-

-

-

0%

Reticulo Endothelial system

01

-

01

1.9%

Table 3

Showing diseases and sex-wise distribution of cases

System & diseases

Male deaths

Female deaths

Total deaths

Central Nervous System

Meningitis

-

Epilepsy

-

01

01

Cardio Vascular System

Acute Myocardial Infarction

18

01

19

Congestive cardiac failure

02

02

Chronic ischemic heart disease

07

01

08

Cardiac arrythmia

01

01

Malignant hypertension

01

01

Cardiac insufficiency/Tumour

02

02

Cardiac arrest

03

03

Gastro Intestinal Tract

Acute Hemorrhagic pancreatitis

001

01

Eosophageal varices rupture

01

01

Chemical peritonitis due to acid peptic disease leading to perforation

00

00

Respirator System

Bronchopulmonary pneumonia

02

00

02

Diffuse alveolar damage

01

01

Acute respiratory Distress Syndrome

03

03

Plueritis

00

00

Chronic obstructive pulmonary disorder

02

02

04

Lobar pneumonia

01

01

Acute trachea bronchitis

01

01

Reticulo Endothelial system- 01[1.9%]

Septicemia/Infections

01

-

01

Total

49

03

52

Table 4

Indicating CNS pathology

System

Diseases

Co-morbid condition

Central Nervous System

Epilepsy

Pulomonary edema

General congestion

Meningitis

-

Table 5

Indicating gastro intestinal system pathology

System

Diseases

Co-morbid condition

Gastro Intestinal Tract

Eosophageal varices rupture

Fatty liver

Portal hypertension

Acute Hemorrhagic pancreatitis

Chronic alcoholism

Chemical peritonitis due to acid peptic disease leading to perforation

Chronic alcoholism

Table 6

Indicating respiratory system pathology

System

Diseases

Co-morbid condition

Respiratory System

Bronchopulmonary pneumonia

Anemia

Chronic ischemic heart disease

Generalised muscular atrophy

Sepsis

Rheumatic heart disease

Hypertension

Diabetes mellitus

Pleural effusion

Malnutrient defficiency

Pyelonephritis

Hepatomegaly

Fatty liver

Cardiomegaly

Cardiac hypertrophy

Chronic gastritis

Chronic alcoholism

ascites

Viral etiology

septecemia

Diffuse alveolar damage

Aplastic anemia

Pulmonary edema

Acute tubular necrosis

Cardiac hypertrophy

Acute respiratory failure

septicemia

Bronchopulmonary pneumonia

Iron deficiency pneumonia

Plueritis

Anemia

malnutrition

Chronic obstructive pulmonary disorder

Generalised debility

Heptalosplenomegaly

Senility

Anemia

Starvation

Lobar pneumonia

Fatty liver

Chronic alcoholism

spilepsy

Acute trachea bronchitis

bronchopneumonia

Fatty liver

Necrotic kidney

Chronic ischemic heart disease

Table 7

Indicating cardio vascular system pathology

System

Diseases

Co-morbid condition

Cardio Vascular System

Acute Myocardial Infarction

Left coronary artery occlusion

Left ventricular wall aneurysm

Dilated cardiomyopathy

Hepatosplenomegaly

Artherosclerosis

Shock lung

Hypertensive heart disease

Coronary artery disease

Obstructive pulomonary disease

Chronic glomerulonephritis

Congestive cardiac failure

Pneumonia

Pleural effusion

Malnutient deficiency

Bronchopneumonia

Pleural adhesion & edema

Fatty degeneration of liver

Chronic pancreatitis

Chronic ischemic heart disease

Broncho pulmonary pneumonia

Chronic alcoholism

Cardiac arrhythmia

Chronic alcoholism

Fatty degeneration of liver

Cirrhosis of liver

Malignant hypertension

Interventricular hemorrhage

Cardiac insufficiency

Narrowing of right coronary artery

Fibroatheroma

cardiomegaly

Cardiac arrest

Complete occlusion of right coronary artery

Atheromatous plagues

Table 8

Comparison of similar studies done Else where.

Studies

% of sudden natural deaths

Male to female ratio

Max frequency age group

Common system involved

Present study

11.61%

16.3:1

40-49

Rs 50%

Sudden natural death in Khartoum Mortuary Elsadig Y. Mohamed, Ahmed Abdelbadie, Sawsun M. Abdalla, Adil A Alsideg, Ammar Hassan Khamis Sudden natural death in Khartoum Mortuary Elsadig Y. Mohamed, Ahmed Abdelbadie, Sawsun M. Abdalla, Adil A Alsideg, Ammar Hassan Khamis Sudden natural death in Khartoum Mortuary Elsadig Y. Mohamed, Ahmed Abdelbadie, Sawsun M. Abdalla, Adil A Alsideg, Ammar Hassan Khamis Sudden natural death in Khartoum Mortuary Elsadig Y. Mohamed, Ahmed Abdelbadie, Sawsun M. Abdalla, Adil A Alsideg, Ammar Hassan Khamis

-

4.9:1

40 and below

RS 49.3%

Sudden & Unexpected Natural Deaths-A four Year Autopsy Review. Dr. Dinesh S Rao Dr. Yadhukul5

8.67%

5.8:1

45-65

CVS 66.67%

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur Virendra Kumar *, Kang Pei San, Anuar Idwan, Norazlan Shah, Siti Hajar, Mohamad Norkahf6

18.8%

6.8:1

41-50

CVS 64.9%

Study of Sudden Natural Deaths in Medico-Legal autopsies wit specific reference to Cardiac Causes. Sandesh H. Chaudhari, Anand Mugadlimath Mandar Sane, K.U. Zine D.I. Ingale, Rekha Hiremath7

9%

4.3:1.

41-50

CVS 44.6%

Causes of sudden natural death in Jamaica: a medicolegal (coroner’s) autopsy study from the University Hospital of West Indies C.T. Escoffery, S.E. Shirley8

51.3%

1.2:1

61-70

CVS 65.5%

Autopsy findings in sudden death in adults: a study of 150 cases Rahul A. Modi, Mubin I. Patel, Mandakini M. Patel, Suresh Padsala, Jainisha Chaudhary9

21.73%

4:1

35-45

CVS 56%

Aims and Objectives

  1. To Study the Contribution of Organs System to Mortality.

  2. To Study the Age & Sec Group involvement in Sudden Deaths.

  3. To understand the Co Morbid Factors contributing to the Sudden Deaths.

Materials and Methods

The present study is a Retrospective Study, all Autopsy reports designated as Sudden and Unexpected Deaths for the period Jan 2017 to June 2022 were Collected and Studied. The Information on Cause of Death and the System Wise Pathology along with Histology reports, was obtained from the Autopsy reports besides, The Information on the circumstances and Past Medical History of the deceased were obtained from those available in the police inquest report and Hospital Records of the Respective Autopsy Records. The Information thus obtained were entered in a standard Performa and the same was analysed and studied. All Sudden Deaths wherein poisons or Unnatural causes were Excluded. onset of the terminal symptoms”.

Results

Sudden and unexpected deaths amounted to 11.61% of medico legal autopsies. Male to female rations was 16.3:1. Maximum incidence of sudden and unexpected deaths was reported above 35 yrs of age, with peak incidence between 41-50 years. Pulmonary pathology contributed 50% to major cause of sudden and unexpected deaths. The co morbid conditions associated with the leading cause of sudden natural deaths are mentioned in table no. 6.

Discussion

In the Present Retrospective Study conducted for the period 2017- June 2022, Sudden and Unexpected Natural Deaths contributed to 11.61%(n-52)(Fig-01) of the total number of Autopsies. The Observations are close to those made by V. Kumar et al.3 and Other studied else

Where,4, 5, 6 who had observed 18.8% of his cases contributing to Sudden Deaths, However majority of his victims studied were Males(87.2%).This results are close to the present study wherein Majority victims were Males(Table no 03)(Fig-02) contributing to 92.31%n-(48) of cases. All this clearly indicates the Male Preponderance in incidences of Sudden and Natural Death.7, 8, 9

In the present Study Majority of the Victims belonged to 4th Decade(Table no 01), contributing to 40.38%(n-21),this observations are similar to those made by Anand Mugadilmath et al.,2 who inferred 30.81% of his victims belonging to similar age group. This findings also are close to the observations made by Meina singh et al.10

The present study also highlights the fact that Cardiovascular System contributed(Table no 02) to the Major number of Sudden Deaths in 69.23%(n-36) of Cases, this observations are consistent with similar studies done by other Researchers else where.11, 12, 13, 14, 15, 16, 17, 18 All this indicates the fact that Cardiac Pathology is the main contributor for the Sudden and Unexpected nature of Deaths.The major comorbidites [Table no 06]observed that contributed to the underlying cause is Smoking, Obesity, Hypertension, Diabetes Mellitus and possible Life Style factor.

The Table no 3,5, 6,7 indicates the different type of Co Morbid Conditions that contributed to the Deaths.

The other major system involved in Sudden Deaths was the Respiratory System(Table no 02) contributing to 23.07%(n-12) of the Deaths, this results are close to the observations made by Anand Mugadilmath et al. 2

The Gastro Intestinal System contributed to 5.77%(n-3) of Sudden Deaths which is in contrast to the studies done by Kuller et al.19 who observed 27.7% of his Victims died due to Gastro intestinal related causes. This wide variations is possible due to the Regional, Cultural and Life Style Factors. The Table no 08 compares similar studies done else where.

This Study Highlights importance of More Research involving the Cardiovascular System to understand the Causes of Death and at the same time prevent such deaths. It also emphasises the facSt that more studies required to understand the Dominance of Male Victims.

Abbrevations

CVS-Cardio Vascular system, CNS-Central Nervous System, RS-Respiratory System. GIT-Gastro Intestinal System, RES-Reticulo Endothelial System; HBS-Hepatobiliary System.

Source of Funding

None.

Conflict of Interest

None.

References

1 

K S Reddy Narayan The Essentials of Forensic Medicine and Toxicology.Medical Book Co. Hyderabad20081334

2 

H Sandesh A Chaudhari R Ingale KUM Sane DI Zine Study of Sudden Natural Deaths in Medico-Legal Autopsies with Special Reference to Cardiac CausesInt J Cur Res Rev2013533742

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V Kumar P San N Shah A Idwan A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala LumpurJ Forensic Legal Med20071431514

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B Knight Knight’s forensic pathology3rd 2004497

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S D Cohle MP Suarez-Mier B Aguilera Sudden death resulting from lesions of the cardiac conduction systemAm J Foren Med Pathol20022318392

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Article type

Original Article


Article page

81-86


Authors Details

Dinesh Rao, Rida Fatima, Kiran


Article History

Received : 13-07-2022

Accepted : 25-08-2022


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